The Story of Pain: From Prayer to Painkillers by Joanna Bourke

By Joanna Bourke

we all know what's sounds like to be in soreness. Scraped knees, toothaches, migraines, giving beginning, melanoma, center assaults, and heartaches: discomfort permeates our complete lives. We additionally witness people - family - agony, and we 'feel with' them.

It is straightforward to imagine this is often the top of the tale: 'pain-is-pain-is-pain', and that's all there's to claim. however it isn't really. actually, the way humans reply to what they describe as 'painful' has replaced significantly through the years. within the eighteenth and 19th centuries, for instance, humans believed that soreness served a selected (and confident) functionality - it was once a message from God or Nature; it is going to excellent the spirit. 'Suffer during this existence and also you would not endure within the subsequent one'.
Submission to discomfort used to be required. not anything might be extra faraway from 20th and twenty-first century understandings, the place discomfort is considered an unremitting evil to be 'fought'.

Focusing at the English-speaking international, this publication tells the tale of ache because the eighteenth century, addressing primary questions on the event and nature of pain over the past 3 centuries. How have these in ache interpreted their discomfort - and the way have those interpretations replaced through the years? How have humans learnt to behavior themselves while pain? How do family and friends react? And what approximately doctors: should still they immerse themselves within the suffering
person or is the simplest reaction a type of specialist detachment?

As Joanna Bourke exhibits during this attention-grabbing research, humans have get a hold of many alternative solutions to those questions over the years. And a heritage of soreness can let us know greatly approximately how we'd reply to our personal agony within the current - and, simply as importantly, to the affliction of these round us.

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Drug-Induced Movement Disorders (Neurological Disease and by Kapil D. Sethi

By Kapil D. Sethi

Drug-Induced circulate problems carefully analyzes demonstrated and rising proof surrounding drug-induced dystonia, dyskinesia, akathisia, parkinsonism, and different acute and tardive circulation issues prone to outcome from medicinal use of dopamine blocking off brokers, antidepressants, levodopa, anticonvulsants, and different drugs-providing pros potent instruments for predicting, deciding upon, and proactively handling those usually treatable, and regularly preventable, conditions.

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Handbook of Neuroemergency Clinical Trials by Wayne M. Alves,Brett E. Skolnick

By Wayne M. Alves,Brett E. Skolnick

through the 1990’s, clinical advances in knowing the mechanisms and pathophysiology of acute principal anxious approach harm have been offset by way of a historical past of disappointing effects from section III medical trials of novel neuroprotective medicinal drugs. a number of novel compounds have been “tested,” and probably fell via the wayside. This ebook is meant to target novel treatments and the original demanding situations their meant goals pose for the layout and research of scientific trials. The authors discover the problems dealing with study during this region and the recommendations that may result in destiny good fortune during this serious zone of unmet clinical want. It represents a compendium of knowledge received from over twenty years of medical trial adventure in components of acute neurology and neurosurgery. From the data of scientific evaluation utilizing standardized instruments, to the complicated layout of inauspicious hyper-acute neuroemergencies trials, the reader will enjoy the authors’ perspectives.

* offers new views on acute neuroemergency medical trials
* contains insights from medical pharmacology and perspectives
* Discusses historic classes realized from early and up to date trials in acute neuroscience populations

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Professionelles Schmerzassessment bei Menschen mit Demenz: by Meike Schwermann,Markus Münch

By Meike Schwermann,Markus Münch

Dieser handlungsorientierte Leitfaden bietet neben einer theoretischen Einführung in das Thema Hinweise und Hilfen zur Einführung, Umsetzung und Weiterentwicklung eines professionellen Schmerzassessments für Menschen mit Demenz. Pflegefachkräfte erhalten einen breiten Überblick über das Thema sowie anwendungsbezogene Hilfestellungen. Führungs- und Lehrkräfte finden in diesem Buch assorted Anregungen, um die Mitarbeiter zu schulen und die Instrumente in einer establishment einzuführen.
In der 2. Auflage wurde insbesondere der erste Abschnitt zur Schmerzerfassung vor dem Hintergrund neuerer Studien und Entwicklungen aktualisiert und überarbeitet.

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Arzneiverordnungs-Report 2009: Aktuelle Daten, Kosten, by Ulrich Schwabe,Dieter (Eds.) Paffrath,Dieter Paffrath

By Ulrich Schwabe,Dieter (Eds.) Paffrath,Dieter Paffrath

Der Arzneiverordnungs-Report ist eines der neuesten Pharmakologiewerke im deutschsprachigen Raum. Er wird jährlich intensiv überarbeitet und ist für Ärzte eine wichtige Entscheidungshilfe in der Pharmakotherapie. Seit nunmehr 25 Jahren analysiert er die Ursachen für die massiv steigenden Ausgaben der gesetzlichen Krankenversicherungen. Datenbasis sind 723 Millionen Verordnungen, die im Jahre 2008 von 135.388 Vertragsärzten rezeptiert wurden. Auch die neuen Arzneistoffe des Jahres 2009 werden pharmakologisch-therapeutisch bewertet. Als Schwerpunktthema werden erstmals die Verordnungen der Impfstoffe analysiert. Presseecho zum Arzneiverordnungs-Report 2008
„Arzneikosten treiben Kassenbeiträge' (Der Tagesspiegel 24.09.2008) „Schmidt setzt Arzneimittelbranche neue Hürden – Kassen sollen neue Medikamente nur noch bezahlen, wenn diese deutlich besser als preiswerte Präparate sind' (Handelsblatt 24.09.2008) „Preistreiberei zu Lasten der Versicherten – Wissenschaftler sehen Einsparpotential von mehreren Milliarden Euro' (Leipziger Volkszeitung 24.09.2008) „Arzneikosten steigen wieder deutlich an – Gesundheitsministerin Schmidt ‚Preistreiberei’ – Medikamente in anderen Ländern oft viel billiger' (Neue Presse Coburg 24.09.2008)

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Biofunktionalität der Lebensmittelinhaltsstoffe by Dirk Haller,Tilman Grune,Gerald Rimbach

By Dirk Haller,Tilman Grune,Gerald Rimbach

Funktionelle Lebensmittel wirken nachweisbar stärker positiv auf die menschliche Gesundheit als normale. Das erste Lehrbuch zum Thema behandelt systematisch die Organfunktionen des Körpers und zeigt die Methoden, mit denen eine präventive Wirkung nachgewiesen werden kann. „Steckbriefe“ aller relevanten Klassen von Lebensmittelinhaltsstoffen und deren Wirksamkeit bieten einen guten Überblick. Ergänzt wird das mit Abbildungen und Themenboxen anschaulich gestaltete Nachschlagewerk für Studenten und Lebensmittelexperten durch zahlreiche Fallbeispiele.

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Deliver Me from Pain: Anesthesia and Birth in America by Jacqueline H. Wolf

By Jacqueline H. Wolf

Despite ultra-modern traditionally low maternal and youngster mortality charges within the usa, exertions keeps to awaken worry between American ladies. instead of embody the common childbirth equipment promoted within the Seventies, most ladies welcome epidural anesthesia or even Cesarean deliveries. In Deliver Me from Pain, Jacqueline H. Wolf asks how a remedy akin to obstetric anesthesia, even if it traditionally posed severe probability to moms and newborns, satirically got here to soothe women's nervousness approximately birth.

Each bankruptcy starts off with the tale of a start, dramatically illustrating the original practices of the period being tested. Deliver Me from Pain covers the advance and use of anesthesia from ether and chloroform within the mid-nineteenth century; to amnesiacs, barbiturates, narcotics, opioids, tranquilizers, saddle blocks, spinals, and gasoline throughout the mid-twentieth century; to epidural anesthesia today.

Labor discomfort isn't purely a physiological reaction, yet a phenomenon that moms and physicians understand via a historic, social, and cultural lens. Wolf examines those affects and argues that scientific and lay perspectives of work soreness and the concomitant popularity of obstetric anesthesia have had a ripple impact, developing the stipulations for recognition of alternative, frequently pointless, and occasionally dicy obstetric remedies: forceps, the chemical induction and augmentation of work, episiotomy, digital fetal tracking, and Cesarean section.

As American ladies make judgements approximately anesthesia this present day, Deliver Me from Pain deals them perception into how girls made this selection some time past and why every one new release of moms has made dramatically varied decisions.

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Drugs for HER-2-positive Breast Cancer (Milestones in Drug by Maria Sibilia,Christoph C. Zielinski,Rupert Bartsch,Thomas

By Maria Sibilia,Christoph C. Zielinski,Rupert Bartsch,Thomas W. Grunt

Growth issue receptors have lengthy been recognized to force malignant transformation and melanoma development. The epidermal progress issue receptor (EGFR, ErbB, HER) method is probably going the simplest defined membrane receptor tyrosine kinase family members in malignant tumors. With implementation of the growth-inhibitory anti-HER-2 antibody trastuzumab (Herceptin) for the remedy of HER-2-positive complicated metastatic breast melanoma, a brand new period has dawned within the remedy of this malignant illness. regrettably, trastuzumab-sensitive cancers normally improve resistance to the antibody after your time. contemporary scientific experiences have printed that those refractory tumors are nonetheless conscious of inhibition of the HER receptor kinfolk utilizing twin HER-1/-2 inhibitors akin to lapatinib (Tykerb/Tyverb). furthermore, a multiplicity of novel, superior irreversibly performing small molecular HER tyrosine kinase inhibitors are within the pipeline of many drug constructing businesses and are being evaluated within the medical setting.

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Kompendium der medikamentösen Schmerztherapie: Wirkungen, by Beubler,Kunz,Sorge,Roland Kunz,Jürgen Sorge

By Beubler,Kunz,Sorge,Roland Kunz,Jürgen Sorge

Das Buch beinhaltet übersichtlich und prägnant eine Zusammenstellung aller in der Schmerztherapie wichtigen Arzneimittel, deren Wirkungen, Nebenwirkungen und Kombinationsmöglichkeiten. Somit leistet es einen wertvollen Beitrag zur Umsetzung einer adäquaten, an die individuelle scenario des Patienten angepassten Schmerztherapie. In der 6. Auflage wurden die Inhalte komplett überarbeitet und auf den aktuellen Wissensstand gebracht. Des Weiteren werden Neuerungen von neuen Arzneiformen für alte, bewährte Arzneisubstanzen vorgestellt. Ferner wird das Nebenwirkungsspektrum intestine bekannter Schmerzmittel neu diskutiert.

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Drugs During Pregnancy: Methodological Aspects by Bengt Källén

By Bengt Källén

This ebook addresses methodological features of epidemiological reports on maternal drug use in being pregnant. Discussing the prevailing assets of mistakes and the way they could produce flawed conclusions, it examines quite a few epidemiological thoughts and assesses their strengths and weaknesses. those refer either to the id of results (with precise emphasis on congenital malformations) and to the categories of publicity (drug use).

Further, the e-book discusses the matter of confounding and the way to address it, and gives an easy creation to statistical data. certain events, e.g. forms of parental publicity, are tested. finally, the e-book discusses pharmacovigilance and the data challenge, concluding with a brief record of points to contemplate whilst one desires to review a broadcast paper within the field. 

Though the booklet is essentially meant for pharmacologists, gynecologists and obstetricians, it is going to profit all medical professionals operating in perinatal care.

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